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scientific advisory board

The Company has established a Scientific Advisory Board comprised of individuals with broad expertise in relevant areas. The advisory board meets at the Company's request to review and evaluate the Company's scientific progress and plans and to identify and evaluate scientific developments that may be of commercial interest to the Company. The members of the Scientific Advisory Board are:

Michael E. DeBakey, M.D., is Chancellor Emeritus, Distinguished Service Professor & Olga Keith Wiess Professor of Surgery, Baylor College of Medicine. Dr. DeBakey's surgical career has earned him world renown as a surgeon, innovator, teacher and medical statesman. While still a medical student, he devised a pump that years later became one of the essential components of the heart-lung machine that made open-heart surgery possible. To date, he has developed more than 50 surgical instruments and is best known for his innovations in treating cardiovascular diseases. He has authored and published more than 1,000 medical articles, chapters, and books. Dr. DeBakey has also served as Chairman of the President's Commission on Heart Disease, Cancer, and Stroke during the Administration of President Lyndon Johnson and as a member on the National Advisory Heart and Lung Council of the National Institutes of Health. Dr. DeBakey also holds memberships and fellowships in numerous medical surgical societies throughout the world and has received honors from many heads of state, including the United States Medal of Freedom, the highest honor the President can bestow on a civilian.

George P. Noon, M.D., is a Professor of Surgery and Chief, Division of Transplant & Assist Devices, Baylor College of Medicine; Executive Director, Multi-Organ Transplant Center, The Methodist Hospital, Houston, Texas. He has been involved in artificial heart research since 1966 and implanted an artificial heart in a Russian patient in 1967 as a Delegate of the United States-U.S.S.R. Artificial Heart Program.

O. H. Frazier, M.D., is the Director, Cardiovascular Surgical Research, Co-Director, Cullen Cardiovascular Research Laboratories, and Chief, Cardiopulmonary Transplantation, Texas Heart Institute; Chief, Transplant Service, St. Luke's Episcopal Hospital. Dr. Frazier is a distinguished surgeon, scientist, and academician who has applied his vast experience to the research and development of new cardiovascular surgical techniques, including the development of artificial heart and circulatory assist devices. His primary clinical interests are cardiopulmonary transplantation and heart assist devices, including total artificial hearts.

Nadim M. Zacca, M.D., is a Clinical Associate Professor of Medicine, Baylor College of Medicine. He has been involved in research related to cardiac catheterization since 1979 and has been the Associate Director and Director of the Catheterization Laboratory at Veterans Administration Hospital, Houston, TX. Dr. Zacca, while at BCM in the mid 1980's, was the core clinical contributor for the development of the original Rotablator®, now sold by Boston Scientific.